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- Steroid hormone receptors
- Cell membrane steroid hormone receptors
- Nuclear receptors coactivators and corepressors
- Steroid hormone receptors non-transcriptional signaling
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MOLECULAR REGULATION OF TARGET TISSUES |
- Direct effects of sex steroid hormones on the vascular wall
- Sex steroid hormones and the central nervous system
- Molecular control of bone synthesis and resorption
- Cellular mechanisms of immune regulation
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INTRACELLULAR SIGNALING PATHWAYS |
- Growth factors signaling cascades in reproductive tissues
- Cytokines and cytokine receptors
- G protein-coupled receptors signaling
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- Angiogenesis during embryo implantation
- Angiogenesis and gynecological cancers
- Angiogenetic processes in the ovary
- Angiogenesis and endometriosis
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HYPOTHALAMO-PITUITARY-OVARIAN AXIS |
- Molecular determinants of gonadotropins biological actions
- FSH and LH receptors
- Polymorphisms and mutations of gonadotropin receptors
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- The IGFs/IGF-BPs/IGF-Rs system
- Molecular regulation of adipocytes by insulin and IGFs
- Insulin sensitivity and reproduction
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NEW TREATMENTS IN GYNECOLOGICAL ENDOCRINOLOGY |
- The future of gene therapy in gynecological endocrinology
- Molecular basis for the actions of estrogens, antiestrogens and selective estrogen receptor modulators
- Molecular differences between GnRH analogs and antagonists
- Molecular basis for the development of new tocolytic agents
- Effects of different progestins on reproductive tissues
- Impact of route of administration on hormone effects
- Selective Progesterone Receptor Modulators (SPRMs)
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- Growth factors and cytokines networks in placental function
- Insulin resistance and obstetric diseases
- Thyroid hormones and pregnancy
- Cytokines and other inflammatory factors in preterm labour
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MEDICALLY ASSISTED PROCREATION |
- Hormonal regulation of embryonic development
- Assisted reproduction for patients with primary and premature ovarian failure
- Ovulation induction
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- DHEA and DHEAS signaling and therapy
- Stress, adrenal gland and menstrual cyclicity
- Molecular regulation of the HPA axis
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- Steroid hormones and cellular ageing processes
- Neurosteroids: reproductive events and ageing
- The androgen deficiency syndrome
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- Postmenopausal osteoporosis
- HRT:cardiovascular disease and cancers
- HRT and Alzheimer and Parkinson Diseases
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THERAPEUTIC INTERVENTIONS IN MENOPAUSE |
- Progesterone, progestins and SPRMs
- Androgen therapy
- Hormonal manipulation of breast tissue
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- Genes and gynecological cancers
- Proteomics as a tool for cancer diagnosis and treatment
- Gene expression in endometrial hyperplasia
- Hormones and gynecological cancers
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- Genetics and hormonal modulation of endometriosis
- Cytokines in endometriosis development
- Novel treatments for endometriosis
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- Non-contraceptive benefits of oral contraceptives
- Ovarian activity under contraception
- Male contraception
- New roots for hormonal contraception
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- The onset of puberty
- Primary amenorrhoea
- Adolescent sexuality
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- Hyperandrogenism in PCOS patients
- Insulin resistance and cardiovascular risk in PCOS
- Insulin-sensitising agents and PCOS
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- Endometrial maturation and abnormal menstrual bleeding
- Hypothalamic dysfunction
- Luteal function and luteal defects
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- Genomic and proteomics in human reproduction
- Molecular mechanisms of follicle selection and development
- Molecular and endocrine regulation of embryo implantation
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